U.S. President Donald Trump has taken one of the most far-reaching foreign policy decisions of his second term by pulling the United States out of 66 international organisations, a move that is already reshaping global governance and opening up significant space for China to expand its influence. The list includes major United Nations bodies as well as the International Solar Alliance (ISA), a flagship initiative led by India and France.
By signing a memorandum titled “Withdrawing the United States from International Organisations, Conventions, and Treaties that Are Contrary to the Interests of the United States”, President Trump formally instructed all U.S. government departments and agencies to begin the withdrawal process immediately. The order makes clear that the exits should be completed “as soon as possible,” marking a decisive break from decades of American engagement with multilateral institutions.
In New Delhi’s assessment, the most immediate impact of the U.S. exit will be felt in two areas: funding and leadership. Many of the organisations affected rely heavily on American financial contributions and political backing. With Washington stepping away, officials believe a leadership vacuum is inevitable — one that China is well-positioned to fill given its financial resources, institutional reach, and growing diplomatic clout.
One of the most consequential exits is from the World Health Organisation (WHO). The U.S. initiated its withdrawal on January 20, 2025, the first day of Trump’s second term, and it is scheduled to become fully effective by January 2026. As the WHO’s largest donor, the U.S. departure will lead to significant funding shortfalls. This could weaken global preparedness for future pandemics, disrupt disease surveillance systems, and affect health programmes in developing countries, including India, particularly those targeting HIV/AIDS, tuberculosis, and malaria.
The U.S. exit from UNESCO, formally notified in July 2025, is expected to create similar challenges. Reduced funding and the absence of American leadership may allow other countries, especially China, to step in and shape agendas related to education, culture, and heritage preservation. The withdrawal also means fewer resources for global heritage conservation and educational initiatives worldwide.
Washington’s decision to leave the UN Human Rights Council (UNHRC) further limits its ability to influence global human rights discourse. With the U.S. no longer participating, countries such as China and Russia may face less resistance in diluting human rights norms and weakening international accountability mechanisms.
Another major fallout involves the UN Relief and Works Agency for Palestine Refugees (UNRWA). After the U.S. suspended all funding in February 2025, the agency’s capacity to deliver humanitarian assistance in Gaza and other Palestinian territories has been severely constrained. India, which has been a consistent contributor to UNRWA, may face pressure to increase its support — a sensitive issue given Israel’s long-standing criticism of the agency.
Broadly, Trump’s latest decision affects two major categories of organisations. The first includes climate and environmental bodies. By exiting not only the Paris Agreement but also foundational treaties like the UN Framework Convention on Climate Change (UNFCCC), the U.S. becomes the first country to withdraw from the core architecture of global climate governance. As one of the world’s largest historical emitters, America’s departure is expected to slow collective climate action and weaken efforts to limit global warming to 1.5°C. It could also embolden other countries to scale back their commitments.
The U.S. withdrawal from the Intergovernmental Panel on Climate Change (IPCC) is particularly significant. The move undermines global climate science by sidelining American researchers and reducing the pool of shared data critical for accurate climate modelling and policymaking — a setback for countries like India that depend on global assessments for planning and adaptation.
For India, the U.S. exit from the International Solar Alliance represents both a practical and symbolic blow. Headquartered in India, the ISA was created to mobilise over $1 trillion in solar investments by 2030. The loss of U.S. participation means reduced funding prospects, diminished technical expertise, and a weakening of global influence, even though the alliance has diversified its membership and financing sources over time.
Other environmental and energy groupings likely to feel the impact include the International Union for Conservation of Nature (IUCN), the International Renewable Energy Agency (IRENA), and initiatives such as the 24/7 Carbon-Free Energy Compact.
The second category affected by Trump’s decision includes economic, development, and human rights institutions. By rejecting the OECD-led global minimum tax deal, the U.S. has injected uncertainty into efforts to curb profit shifting by multinational corporations. Without participation from the world’s largest economy, implementing the global tax framework becomes far more difficult.
Additional organisations facing disruption include the UN Population Fund (UNFPA), UN Women, and the UN Conference on Trade and Development (UNCTAD), all of which play critical roles in development, gender equality, and global trade governance.
Also targeted are institutions that uphold the rules-based international order, such as the International Law Commission, the UN Peacebuilding Commission, the Venice Commission, and the Global Counterterrorism Forum. The withdrawal extends to key UN economic and regional bodies under ECOSOC, as well as offices dealing with children in armed conflict.
Indian officials believe many of these institutions are now “ripe for picking” by Beijing. As the U.S. steps back, India and other like-minded countries will need to coordinate closely to preserve global norms, protect institutional integrity, and prevent the erosion of the rules-based order.